Challenge your young math wizards to solve this multiply 100 and 4-digit numbers worksheet. When asked to multiply numbers with zeros, students love it. They realize they may disregard the zero during calculations and only include it again when recording the result. There is a lot of practice with this concept in the multiply 100 and 4-digit numbers worksheet. This worksheet is about practicing the column method in which numbers are written one on top of another. In this method, students use their place value understanding to solve the problems.